Milk Thistle Seed Extract 100% Silymarin Powder

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About this item
100% NATURAL PRODUCT: No artificial colors or flavors Verified herb identity, confirmed highest quality of raw materials and the extract Best natural sources of herbs and raw materials: Every vendor is carefully picked to meet our high standards Third-party lab tested, All natural Milk Thistle Extract Liver Cleanse Detox Milk thistle (Silybum marianum) is a medicinal plant from the Asteraceae family. Silymarin is the major constituent of milk thistle extract and is a mixture of some flavonolignans such as silybin, which is the most active component of silymarin. It is most commonly known for its hepatoprotective effect.
Keywords: Silybum marianum; Silymarin; GLP-1; Silibinin;

Contaminants
Arsenic (As)	≤ 0.5 mg/kg	Conforms	GB 5009.76
Lead (Pb)	≤ 0.5 mg/kg	Conforms	GB 5009.75
Mercury (Hg)	≤ 0.1 mg/kg	Conforms	GB 5009.17
Cadmium(Cd)	≤ 0.5 mg/kg	Conforms	GB 5009.15
Residual Acetone	≤ 5,000 μg/g	3.4x10³μg/g	USP42
Residual Hexane	≤ 290 μg/g	16 μg/g	USP42
Pesticide Residues	Meet Reg. (EC) No 396/2005	Conforms	Reg. (EC) No 396/2005

Microbiological
Total Plate Count	≤ 1,000 cfu/g	Conforms	GB 4789.2
Mold&Yeast	≤ 100 cfu/g	Conforms	GB 4789.15
E. Coli	<10 cfu/g	Conforms	GB 4789.38
Salmonella	Absent/25g	Conforms	GB 4789.4
Staphylococcus aureus	<10 cfu/g	Conforms	GB4789.10
Irradiation status	Non irradiated, No ETO treated, Negative by PSL screen test.
GMO/BSE Status	Non-GMO, Free of BSE.

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* The statements in this section have not been evaluated by the FDA or EFSA.
References
1. Fallah M, Davoodvandi A, Nikmanzar S, et al. Silymarin (milk thistle extract) as a therapeutic agent in gastrointestinal cancer. Biomed Pharmacother. 2021;142:112024. doi:10.1016/j.biopha.2021.112024 2. Wang J, Zhang L, Cao H, et al. Silibinin improves L-cell mass and function through an estrogen receptor-mediated antioxidative mechanism. Phytomedicine. 2022;99:154022. doi:10.1016/j.phymed.2022.154022
3. Zheng N, Liu L, Liu WW, et al. Crosstalk of ROS/RNS and autophagy in silibinin-induced apoptosis of MCF-7 human breast cancer cells in vitro. Acta Pharmacol Sin. 2017;38(2):277-289. doi:10.1038/aps.2016.117
4. Wang J, Zhang X, Zhang L, et al. Silychristin A activates Nrf2-HO-1/SOD2 pathway to reduce apoptosis and improve GLP-1 production through upregulation of estrogen receptor α in GLUTag cells. Eur J Pharmacol. 2020;881:173236. doi:10.1016/j.ejphar.2020.173236

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